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This study was a part of the 2019 Summer Student Research Fellows Program, which has the requirement of presentation at the Symposium. The purpose of this study was to discover the impact of six-week therapeutic hand drumming protocol on the perceived stress levels and an immune system marker of college students during summer session classes. Subjects included college students who volunteered to participate. In the first session, participants were administered the PSS (Perceived Stress Scale) participants’ saliva samples were taken to measure cortisol levels pre and post therapeutic intervention.. After six weeks of drumming sessions, the saliva samples were collected and the PSS administered. Substantial reduction of perceived stress levels were noted as well as a reduction in cortisol level in samples that were usable.